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antibody yy1 61779  (Active Motif)


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    Active Motif antibody yy1 61779
    Antibody Yy1 61779, supplied by Active Motif, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/yy1+antibody+61779/pm39721581-349-27-28?v=Active+Motif
    Average 90 stars, based on 1 article reviews
    antibody yy1 61779 - by Bioz Stars, 2026-08
    90/100 stars

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    antibody yy1 61779  (Active Motif)
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    Active Motif antibody yy1 61779
    Antibody Yy1 61779, supplied by Active Motif, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
    Yy1 Antibody (Pab) 61779, supplied by Active Motif, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    yy1 antibody 61779  (Active Motif)
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    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
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    yy1 61779 antibody  (Active Motif)
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    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
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    antibody yy1 catalog no. 61779  (Active Motif)
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    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
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    yy1 #61779 antibody  (Active Motif)
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    Active Motif yy1 #61779 antibody
    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
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    protein a+g magnetic beads coupled with anti-yy1 antibody #61779  (Active Motif)
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    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with <t>YY1</t> in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.
    Protein A+G Magnetic Beads Coupled With Anti Yy1 Antibody #61779, supplied by Active Motif, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    A. EBNA-LP and EBNA2 localized sites on chromatin overlap with YY1 in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.

    Journal: PLOS Pathogens

    Article Title: Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation

    doi: 10.1371/journal.ppat.1011950

    Figure Lengend Snippet: A. EBNA-LP and EBNA2 localized sites on chromatin overlap with YY1 in LCLs by publicly available ChIP-Seq data. B . Location on chromatin of overlapping peaks between YY1, EBNA-LP, and EBNA2. C . Location on chromatin of overlapping peaks between exclusively YY1 and EBNA-LP. D . Heatmap of YY1 peaks gained in WT LCLs compared to LPKO (dark blue), or shared across WT and LPKO LCLs (light blue) in Donors 6 and 7. E . Gene Set Enrichment Analysis of YY1 peaks unique to WT LCLs compared to RNA-seq gene expression of WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value. F. Relative frequency of CD46 negative cells when total B cells were transfected with Cas9/gRNA complex targeting control surface marker CD46 or CD46 and YY1 prior to infection. G. Relative frequency of CD46 negative naïve B cells with CD46 or CD46 and YY1 knockout prior to infection. F and G experiments were statistically analyzed by two-way ANOVA followed by Sidak post-hoc test. *** indicates p-values < 0.001, **** indicates p-values < 0.0001.

    Article Snippet: YY1 antibody (pAb) , Active Motif , 61779 , 1:1000, western blot.

    Techniques: ChIP-sequencing, RNA Sequencing, Gene Expression, Transfection, Control, Marker, Infection, Knock-Out

    A. Endogenous co-immunoprecipitation in LCLs to YY1. White circles indicate EBNA-LP specific bands. BJAB, an EBV-negative cell line, was used as a negative control. Signal in BJAB lanes indicate non-specific background bands. W indicates the number of W domain in the indicated isoform. B. FLAG-EBNALP co-immunoprecipitation in LPKO LCLs (Donor 4) generated from trans-complementation of total B cells with vector control, wild type, or LRM mutant EBNA-LP. Signal is quantified below band. C . YY1 co-immunoprecipitation in trans-complemented LPKO LCLs. D. Venn diagram of YY1 peaks identified by Cut&Run in LPKO trans-complemented LCLs (Donor 4). E. Heatmap of the identified 671 core YY1 binding sites shared across all three conditions. F. Gene set enrichment analysis of genes associated with YY1 peaks that are significantly enriched in LPKO LCLs trans-complemented with wild type EBNA-LP compared to LRM mutant against the differentially expressed genes in WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value.

    Journal: PLOS Pathogens

    Article Title: Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation

    doi: 10.1371/journal.ppat.1011950

    Figure Lengend Snippet: A. Endogenous co-immunoprecipitation in LCLs to YY1. White circles indicate EBNA-LP specific bands. BJAB, an EBV-negative cell line, was used as a negative control. Signal in BJAB lanes indicate non-specific background bands. W indicates the number of W domain in the indicated isoform. B. FLAG-EBNALP co-immunoprecipitation in LPKO LCLs (Donor 4) generated from trans-complementation of total B cells with vector control, wild type, or LRM mutant EBNA-LP. Signal is quantified below band. C . YY1 co-immunoprecipitation in trans-complemented LPKO LCLs. D. Venn diagram of YY1 peaks identified by Cut&Run in LPKO trans-complemented LCLs (Donor 4). E. Heatmap of the identified 671 core YY1 binding sites shared across all three conditions. F. Gene set enrichment analysis of genes associated with YY1 peaks that are significantly enriched in LPKO LCLs trans-complemented with wild type EBNA-LP compared to LRM mutant against the differentially expressed genes in WT and LPKO LCLs. NES = normalized enrichment score. FDR = false discovery rate q-value.

    Article Snippet: YY1 antibody (pAb) , Active Motif , 61779 , 1:1000, western blot.

    Techniques: Immunoprecipitation, Negative Control, Generated, Plasmid Preparation, Control, Mutagenesis, Binding Assay

    Reagents and materials used in methods.

    Journal: PLOS Pathogens

    Article Title: Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation

    doi: 10.1371/journal.ppat.1011950

    Figure Lengend Snippet: Reagents and materials used in methods.

    Article Snippet: YY1 antibody (pAb) , Active Motif , 61779 , 1:1000, western blot.

    Techniques: Concentration Assay, Purification, Western Blot, Immunofluorescence, Flow Cytometry, Protease Inhibitor